RAF1 Rabbit Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
RAF1 Rabbit Polyclonal Antibody

RAF1 Rabbit Polyclonal Antibody

商家询价

产品名称: RAF1 Rabbit Polyclonal Antibody

英文名称: RAF1 Rabbit Polyclonal Antibody

产品编号: K000318P

产品价格: null

产品产地: 北京市通州区马驹桥

品牌商标: solarbio

更新时间: 2025-01-14T14:04:38

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Anti-RAF1 Polyclonal Antibody

品牌:solarbio | 货号:K000318P

商品货号:商品品牌:规格基本售价:选择规格
K000318P-50ulsolarbio50ul960.00元
K000318P-100ulsolarbio100ul1600.00元
英文名称Anti-RAF1 Polyclonal Antibody
别名CMD1NN;CRAF;NS5;Raf-1;c-Raf
应用WB IHC IF
稀释比例WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
蛋白分子量73kDa
Gene ID5894
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, 
pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human RAF1
性状液体
Public 
Immunogen 
Range
Recombinant protein of human RAF1
Subcellular 
Locations
Cell membrane Cytoplasm Mitochondrion Nucleus
Swiss ProtP04049
克隆类型Polyclonal Antibody
背景资料This gene is the cellular homolog of viral raf gene (v-
raf). The encoded protein is a MAP kinase kinase 
kinase (MAP3K), which functions downstream of the 
Ras family of membrane associated GTPases to which 
it binds directly. Once activated, the cellular RAF1 
protein can phosphorylate to activate the dual 
specificity protein kinases MEK1 and MEK2, which in 
turn phosphorylate to activate the serine/threonine 
specific protein kinases, ERK1 and ERK2. Activated 
ERKs are pleiotropic effectors of cell physiology and 
play an important role in the control of gene 
expression involved in the cell division cycle,apoptosis, 
cell differentiation and cell migration. Mutations inthis 
gene are associated with Noonan syndrome 5 and 
LEOPARD syndrome 2.