RAF1 Rabbit Polyclonal Antibody
产品名称: RAF1 Rabbit Polyclonal Antibody
英文名称: RAF1 Rabbit Polyclonal Antibody
产品编号: K000318P
产品价格: null
产品产地: 北京市通州区马驹桥
品牌商标: solarbio
更新时间: 2025-01-14T14:04:38
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
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Anti-RAF1 Polyclonal Antibody
品牌:solarbio | 货号:K000318P
商品货号: 商品品牌: 规格 基本售价: 选择规格 K000318P-50ul solarbio 50ul 960.00元 K000318P-100ul solarbio 100ul 1600.00元
英文名称 Anti-RAF1 Polyclonal Antibody 别名 CMD1NN;CRAF;NS5;Raf-1;c-Raf 应用 WB IHC IF 稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200. 蛋白分子量 73kDa Gene ID 5894 保存 Store at -20°C. Avoid freeze / thaw cycles. 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol,
pH7.3. 纯化方法 Affinity purification 亚型 IgG 免疫原 Recombinant protein of human RAF1 性状 液体 Public
Immunogen
Range Recombinant protein of human RAF1 Subcellular
Locations Cell membrane Cytoplasm Mitochondrion Nucleus Swiss Prot P04049 克隆类型 Polyclonal Antibody 背景资料 This gene is the cellular homolog of viral raf gene (v-
raf). The encoded protein is a MAP kinase kinase
kinase (MAP3K), which functions downstream of the
Ras family of membrane associated GTPases to which
it binds directly. Once activated, the cellular RAF1
protein can phosphorylate to activate the dual
specificity protein kinases MEK1 and MEK2, which in
turn phosphorylate to activate the serine/threonine
specific protein kinases, ERK1 and ERK2. Activated
ERKs are pleiotropic effectors of cell physiology and
play an important role in the control of gene
expression involved in the cell division cycle,apoptosis,
cell differentiation and cell migration. Mutations inthis
gene are associated with Noonan syndrome 5 and
LEOPARD syndrome 2.
商品货号: | 商品品牌: | 规格 | 基本售价: | 选择规格 |
---|---|---|---|---|
K000318P-50ul | solarbio | 50ul | 960.00元 | |
K000318P-100ul | solarbio | 100ul | 1600.00元 |
英文名称 | Anti-RAF1 Polyclonal Antibody |
---|---|
别名 | CMD1NN;CRAF;NS5;Raf-1;c-Raf |
应用 | WB IHC IF |
稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
蛋白分子量 | 73kDa |
Gene ID | 5894 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human RAF1 |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human RAF1 |
Subcellular Locations | Cell membrane Cytoplasm Mitochondrion Nucleus |
Swiss Prot | P04049 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene is the cellular homolog of viral raf gene (v- raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle,apoptosis, cell differentiation and cell migration. Mutations inthis gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. |